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KMID : 0391319940040020203
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Korean Journal of Biological Response Modifiers
1994 Volume.4 No. 2 p.203 ~ p.208
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Induction Chemotherapy with BH-AC plus Idarubicin in Acute Myelogenous Leukemia: Newly desingned Induction Regimen
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김동욱
한치화/김학기/김춘추/김동집/김준석/김형준/국훈/황태주
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Abstract
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In an attempt to establish the therapeutic effect of BH-AC(N4-behenoy1-l-β-D-arabinofuranosyl cytosine) for acute myelogenous leukemia(AML), the effects of newly designed induction chemotherapy using BH-AC plus Idarubicin have been studied in a
prospective cooperative multi-center trial. The 10 institutions were involved in this study. Since March, 1994 to October, 1994, 32 patients with AML, previously untreated in 22(73.3%) out of 30 evaluable patients. Also, side effects of the BH-AC
plus
Idarubicin regimen were evaluated, yet these effects were mild to moderae in severity and acceptable. The results of this study indicate a definite efficacy of BH-AC plus Idarubicin regimen for induction treatment of AML.
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KEYWORD
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